Changes in the defined daily dose; CYP2D6/CYP3A metabolism as an indicator for dose-setting problems

Evaluation of Aminoglycosides Consumption in Open Heart Surgery Based on the Defined Daily Dose Index

Background: Resistance to antibiotics, including aminoglycosides  (AMG) is one of the problems associated with inappropriate administration of broad-spectrum antibiotics. Objectives: This study aimed to assess the clinical features of aminoglycosides consumption based on the Defined Daily Dose (DDD) index in open heart surgery. Methods: This study was done on 268 patients who underwent heart s...

Review of the use of defined daily dose concept in drug utilisation research in China.

PURPOSE This study aimed to understand the characteristics of drug utilisation researches (DURs) using concepts of defined daily dose in China and to provide further suggestion for future DURs in China. METHODS DURs using concepts of defined daily dose published in China were identified from China Journal Full-text Database, and in-depth data analysis was conducted for DURs published in every...

RELAPSE RATE IN DAILY SINGLE-DOSE PREDNISOLONE THERAPY FOR CHILDREN WITH PRIMARY NEPHROTIC SYNDROME

Most current references recommend divided doses of prednisolone for the initial treatment of idiopathic minimal change nephrotic syndrome in children, with relapse occuring in the majority of them, but there is little experience concerning single-dose prednisolone therapy, especially considering the relapse rate. In this prospective study on 36 consecutive children with primary nephrotic s...

Maximum daily dose of hydrocodone.

General practice fundholding: observations on prescribing patterns and costs using the defined daily dose method.

OBJECTIVE To compare prescribing patterns between a group of fundholding practices and a group of non-fundholding practices in north east Scotland using a method which provides more accurate statements about volumes prescribed than standard NHS statistics. DESIGN The pharmacy practice division of the National Health Service in Scotland provided data for selected British National Formulary sec...